The ship National Geographic Quest at dusk Capurgana, Colombia
The ship National Geographic Quest at dusk Capurgana, Colombia
ExpeditionsPanama and Colombia: Exploring the Caribbean Coast

Panama and Colombia: Exploring the Caribbean Coast 

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Explore the vibrant Caribbean coast of Panama and Colombia aboard the aptly designed National Geographic Quest, where every day offers a new natural or cultural encounter. Hike through lush rainforests alive with wildlife, kayak and Zodiac into hidden inlets, and engage with Indigenous communities from the island-dwelling Guna Yala to the famed artisans of Tuchín. In Fall 2025-Spring 2027 only, enjoy a special opportunity to transit the legendary Panama Canal—an iconic passage linking two great oceans. 

Highlights

Two Guna women, one of the very first indigenous groups to achieve autonomy in Latin America, sell their textiles at a local market in Guna Yala, Panama
  • Visit the palm-shaded Panamanian archipelago of Guna Yala (formerly San Blas Islands), an autonomous province that is home to the Guna people, and get immersed in local culture

  • Discover the coastal treasures and remote wilderness of Colombia, exploring vibrant villages, pristine beaches, and wildlife-rich jungles

  • Explore Colombia's rainforests, brimming with roughly 1,900 bird species, like the Emerald Toucanet and Passerines, and more than 450 fascinating mammals, like the Brown-throated Three-toed Sloth and Northern Tamandua

  • Search for vibrant reef fish, rays, and sea turtles while snorkeling the clear waters surrounding the coral-rich islands of Guna Yala

  • In Fall 2025-Spring 2027 only, transit the Panama Canal over two days to see it by day and in the coolness of night

From

$5,805

/ per person

Was $6,450Save $645

Does not include any flights

duration
8 Days

View our brochure for more details

Central America

Talk to an Expedition Specialist1.800.397.3348

From

$5,805

/ per person

Was $6,450Save $645

duration
8 Days

View our brochure for more details

Central America

From

$5,805

/ per person

Was $6,450Save $645

duration
8 Days

View our brochure for more details

Central America

Itinerary

Multiple routes available

Some departures follow a modified itinerary. Please refer to departure dates for exact routing of your departure.

Download Itinerary

Starts atPanama City, Panama
Ends atCartagena, Colombia

Day 1

Panama City, Panama / Balboa / Embark Ship

Arrive in Panama City, the capital of Panama, this afternoon. Transfer to Port Balboa to embark the National Geographic Quest this evening. You may opt for a culturally immersive pre-voyage extension in Panama City and San Lorenzo, a UNESCO-designated World Heritage Site.

Arrival Time: Arrive before 2:00 p.m. local time.
Arrival City: Panama City, Panama

Meals Included: Dinner

Day 1

Panama City, Panama / Balboa / Embark Ship

Arrive in Panama City, the capital of Panama, this afternoon. Transfer to Port Balboa to embark the National Geographic Quest this evening. You may opt for a culturally immersive pre-voyage extension in Panama City and San Lorenzo, a UNESCO-designated World Heritage Site.

Arrival Time: Arrive before 2:00 p.m. local time.
Arrival City: Panama City, Panama

Meals Included: Dinner

Day 2

Gatún Lake / Barro Colorado / Panama Canal Crossing

Special permission allows the ship to anchor overnight in the Panama Canal’s vast Gatún Lake. Disembark in the morning at Barro Colorado, an island formed by the damming of the Chagres River to build the Panama Canal. A visit to the Smithsonian Tropical Research Institute unveils initiatives to protect and study the extraordinary biodiversity of one of the planet’s most studied tropical forests and site of National Geographic studies.   

Alternatively, engage in the wildness of the region by taking a hike into the jungle, a Zodiac across the vast lake or a boat ride to the mouth of the Chagres to explore the Panama Rainforest Discovery Center. The luminosity of the evening heightens the drama of your transit through the complex lock system of the legendary Panama Canal, 50 miles long and passage for some 14,000 ships yearly. 

Meals Included: Breakfast, Lunch, Dinner

Day 2

Gatún Lake / Barro Colorado / Panama Canal Crossing

Special permission allows the ship to anchor overnight in the Panama Canal’s vast Gatún Lake. Disembark in the morning at Barro Colorado, an island formed by the damming of the Chagres River to build the Panama Canal. A visit to the Smithsonian Tropical Research Institute unveils initiatives to protect and study the extraordinary biodiversity of one of the planet’s most studied tropical forests and site of National Geographic studies.   

Alternatively, engage in the wildness of the region by taking a hike into the jungle, a Zodiac across the vast lake or a boat ride to the mouth of the Chagres to explore the Panama Rainforest Discovery Center. The luminosity of the evening heightens the drama of your transit through the complex lock system of the legendary Panama Canal, 50 miles long and passage for some 14,000 ships yearly. 

Meals Included: Breakfast, Lunch, Dinner

Day 3

Portobelo

In the morning, arrive at the historic town of Portobelo, or “beautiful port,” so named in 1502 by Christopher Columbus and a critical Spanish trading center in the New World. Explore 17th- and 18th-century Spanish fortifications, designated a UNESCO site. Later, hike the surrounding jungle in search of native parrots and unruly howler monkeys.

Meals Included: Breakfast, Lunch, Dinner

Day 3

Portobelo

In the morning, arrive at the historic town of Portobelo, or “beautiful port,” so named in 1502 by Christopher Columbus and a critical Spanish trading center in the New World. Explore 17th- and 18th-century Spanish fortifications, designated a UNESCO site. Later, hike the surrounding jungle in search of native parrots and unruly howler monkeys.

Meals Included: Breakfast, Lunch, Dinner

Day 4

Guna Yala Archipelago

Wake up and find yourself amidst the Guna Yala archipelago (known also as the San Blas Islands), a scattering of 368 tiny, white-sand isles off the northeast coast of Panama. Spend the day exploring paradise where the Guna people still live as their ancestors did–in thatched huts making ancient handicrafts such as molas, colorful panels of stitched fabric. Deeply committed to their culture, the Guna are admired as a politically autonomous community where women make the rules. 

In the afternoon, go offshore and explore the vibrant marine world of this breathtaking utopia by snorkel, kayak and stand-up paddleboard.  

Meals Included: Breakfast, Lunch, Dinner

Day 4

Guna Yala Archipelago

Wake up and find yourself amidst the Guna Yala archipelago (known also as the San Blas Islands), a scattering of 368 tiny, white-sand isles off the northeast coast of Panama. Spend the day exploring paradise where the Guna people still live as their ancestors did–in thatched huts making ancient handicrafts such as molas, colorful panels of stitched fabric. Deeply committed to their culture, the Guna are admired as a politically autonomous community where women make the rules. 

In the afternoon, go offshore and explore the vibrant marine world of this breathtaking utopia by snorkel, kayak and stand-up paddleboard.  

Meals Included: Breakfast, Lunch, Dinner

Day 5

Capurgana and Sapzurro, Colombia

National Geographic Quest calls at the wonderfully isolated villages of Sapzurro and Capurgana positioned only 3 miles apart on the stunning coast of Caribbean Colombia. Set out on a nature walk on the Capurgana-Sapzurro trail. In this area, the ranges of two species of howler monkeys overlap as both the mantled and the Colombian red howler monkeys are here. Watch for toucans, parrots, trogons, occasionally scarlet macaws and possibly three-toed sloths as you traverse the tropical forest trails between the villages. Or choose a shorter hike which takes you across an international, transcontinental frontier to Panama.

Walk through the border crossing, perched high on a bluff, before descending to the beach at the Panamanian village of La Miel. The sheltered waters of the bay at Sapzurro back in Colombia beckon for a pleasant kayak or paddleboard around this tropical inlet. Finish the day at sunset in the village of Capurgana.

Meals Included: Breakfast, Lunch, Dinner

Day 5

Capurgana and Sapzurro, Colombia

National Geographic Quest calls at the wonderfully isolated villages of Sapzurro and Capurgana positioned only 3 miles apart on the stunning coast of Caribbean Colombia. Set out on a nature walk on the Capurgana-Sapzurro trail. In this area, the ranges of two species of howler monkeys overlap as both the mantled and the Colombian red howler monkeys are here. Watch for toucans, parrots, trogons, occasionally scarlet macaws and possibly three-toed sloths as you traverse the tropical forest trails between the villages. Or choose a shorter hike which takes you across an international, transcontinental frontier to Panama.

Walk through the border crossing, perched high on a bluff, before descending to the beach at the Panamanian village of La Miel. The sheltered waters of the bay at Sapzurro back in Colombia beckon for a pleasant kayak or paddleboard around this tropical inlet. Finish the day at sunset in the village of Capurgana.

Meals Included: Breakfast, Lunch, Dinner

Day 6

Santa Cruz de Lorica / San Antero / Tuchín

Visit Santa Cruz de Lorica on the banks of the Sinú River, a melting pot of cultures from throughout Europe and the Middle East. Stroll the central square and notice how the city’s distinct influences live harmoniously, spotlighted in the architecture of the stunning Spanish-colonial cathedral and historic buildings in colorful Arabic styles. A folkloric show will be performed on the riverfront malecón during your walking tour.

Enjoy lunch at a local restaurant before traveling to the nearby indigenous village of Tuchín. Watch craftsmen as they make hats that are considered Colombia’s national symbol, the sombrero vueltiao, and meet the local Zenú, celebrated for their ingenious irrigation systems.  

National Geographic Quest will remain anchored in San Antero overnight. Pending conditions, guests may visit Tuchín in the morning, and Santa Cruz de Lorica in the afternoon.

Meals Included: Breakfast, Lunch, Dinner

Day 6

Santa Cruz de Lorica / San Antero / Tuchín

Visit Santa Cruz de Lorica on the banks of the Sinú River, a melting pot of cultures from throughout Europe and the Middle East. Stroll the central square and notice how the city’s distinct influences live harmoniously, spotlighted in the architecture of the stunning Spanish-colonial cathedral and historic buildings in colorful Arabic styles. A folkloric show will be performed on the riverfront malecón during your walking tour.

Enjoy lunch at a local restaurant before traveling to the nearby indigenous village of Tuchín. Watch craftsmen as they make hats that are considered Colombia’s national symbol, the sombrero vueltiao, and meet the local Zenú, celebrated for their ingenious irrigation systems.  

National Geographic Quest will remain anchored in San Antero overnight. Pending conditions, guests may visit Tuchín in the morning, and Santa Cruz de Lorica in the afternoon.

Meals Included: Breakfast, Lunch, Dinner

Day 7

Cispatá Bay / Sanguare Natural Reserve

The day begins by exploring Cispatá Bay, where you’ll spend the morning among the most extensive area of mangroves on Colombia’s Caribbean coast. Local community guides accompany you to share their insight and knowledge of the prolific wildlife. Join naturalists from local conservation group Asocaiman as they release rehabilitated young caimans back into the wild.

After lunch on board, venture over to the Sanguare Natural Reserve. This former cattle ranch, now part of the national system of protected areas, offers great opportunities to explore on foot or by water. Learn of the conservation work being done and explore the tropical dry forests, coastal lagoons and sea grass beds. Enjoy kayaking or paddleboarding, or dig your toes in the sand and sip a chilled refreshment.

Meals Included: Breakfast, Lunch, Dinner

Day 7

Cispatá Bay / Sanguare Natural Reserve

The day begins by exploring Cispatá Bay, where you’ll spend the morning among the most extensive area of mangroves on Colombia’s Caribbean coast. Local community guides accompany you to share their insight and knowledge of the prolific wildlife. Join naturalists from local conservation group Asocaiman as they release rehabilitated young caimans back into the wild.

After lunch on board, venture over to the Sanguare Natural Reserve. This former cattle ranch, now part of the national system of protected areas, offers great opportunities to explore on foot or by water. Learn of the conservation work being done and explore the tropical dry forests, coastal lagoons and sea grass beds. Enjoy kayaking or paddleboarding, or dig your toes in the sand and sip a chilled refreshment.

Meals Included: Breakfast, Lunch, Dinner

Day 8

Cartagena / Disembark Ship

Disembark in Cartagena and transfer to the airport for flights home.

Departure Time: Depart after 1:00 p.m. local time.
Departure City: Cartagena, Colombia

Meals Included: Breakfast

Day 8

Cartagena / Disembark Ship

Disembark in Cartagena and transfer to the airport for flights home.

Departure Time: Depart after 1:00 p.m. local time.
Departure City: Cartagena, Colombia

Meals Included: Breakfast

Video

Explore with NG Experts: Jennifer Davidson

  • Aug 2023

Explore with National Geographic Expert Jennifer Davidson as she creates connections in Colombia and Panama.

Ships

Ship National Geographic Quest

National Geographic Quest

GUESTS 100

CABINS 50

DECKS 4

National Geographic Quest was purpose-built to explore the Americas, her design and engineering informed by nearly 40 years of experience in these regions.

VIEW SHIP

Expedition Team

Our captains, crew, staff and guides make up the most experienced team in the industry—committed to making every voyage unforgettable. Veteran captains, with decades at sea, are experts at navigating in all conditions, while seasoned naturalists bring advanced knowledge in fields such as geology, wildlife biology and climate science. Many of these professionals have been with us for decades, and their insights bring each destination to life in ways that profoundly enrich your journey. Their expertise is the foundation for the meaningful and transformative experiences we offer in the world’s most extraordinary places.

Captain Andrew Cook with guests and Staff on the Bridge of National Geographic Venture, Baja California, Mexico

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